Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fbln5 (fibulin 5) Rattus norvegicus
Analyze
Symbol: Fbln5
Name: fibulin 5
Description: Predicted to have integrin binding activity; protein C-terminus binding activity; and protein homodimerization activity. Involved in regulation of cell growth. Localizes to the extracellular space. Predicted to colocalize with the elastic fiber. Human ortholog(s) of this gene implicated in age related macular degeneration; autosomal dominant cutis laxa 2; autosomal recessive cutis laxa type IA; and cutis laxa. Orthologous to human FBLN5 (fibulin 5); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dance; developmental arteries and neural crest EGF-like protein; embryonic vascular EGF repeat-containing protein; EVEC; FIBL-5; fibulin-5
Orthologs:
Homo sapiens (human) : FBLN5 (fibulin 5)  HGNC  Alliance
Mus musculus (house mouse) : Fbln5 (fibulin 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbln5 (fibulin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBLN5 (fibulin 5)
Canis lupus familiaris (dog) : FBLN5 (fibulin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbln5 (fibulin 5)
Sus scrofa (pig) : FBLN5 (fibulin 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06125,644,797 - 125,723,957 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,644,804 - 125,723,944 (-)Ensembl
Rnor_5.06134,856,694 - 134,935,853 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46126,018,541 - 126,098,234 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16126,022,288 - 126,102,052 (-)NCBI
Celera6118,399,373 - 118,476,665 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fbln5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2594
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.