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Gene: Fbp1 (fructose-bisphosphatase 1) Rattus norvegicus
Symbol: Fbp1
Name: fructose-bisphosphatase 1
CRRD ID: 2595
Description: Exhibits fructose 1,6-bisphosphate 1-phosphatase activity and monosaccharide binding activity. Involved in cellular response to insulin stimulus; fructose 6-phosphate metabolic process; and gluconeogenesis. Localizes to cytosol. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Orthologous to human FBP1 (fructose-bisphosphatase 1); PARTICIPATES IN gluconeogenesis pathway; glycolysis/gluconeogenesis pathway; fructose and mannose metabolic pathway; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; 1-benzylpiperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; FBPase 1; Fdp; Fructose-1,6- biphosphatase; fructose-1,6- biphosphatase 1; fructose-1,6-bisphosphatase 1; Fructose-16- biphosphatase; fructose-16-bisphosphatase 1; liver FBPase
Homo sapiens (human) : FBP1 (fructose-bisphosphatase 1)  HGNC  Alliance
Mus musculus (house mouse) : Fbp1 (fructose bisphosphatase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbp1 (fructose-bisphosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FBP1 (fructose-bisphosphatase 1)
Canis lupus familiaris (dog) : FBP1 (fructose-bisphosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbp1 (fructose-bisphosphatase 1)
Sus scrofa (pig) : FBP1 (fructose-bisphosphatase 1)
Chlorocebus sabaeus (African green monkey) : FBP1 (fructose-bisphosphatase 1)
Heterocephalus glaber (naked mole-rat) : Fbp1 (fructose-bisphosphatase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.017396,175 - 417,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl17396,180 - 417,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.017391,323 - 412,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,795,717 - 7,818,041 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1177,795,716 - 7,818,038 (+)NCBI
Celera17294,875 - 316,917 (-)NCBICelera
Cytogenetic Map17p14NCBI
RH 3.4 Map175.6RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fbp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2595
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.