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Gene: Fga (fibrinogen alpha chain) Rattus norvegicus
Symbol: Fga
Name: fibrinogen alpha chain
Description: Predicted to contribute to cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; liver regeneration; and response to peptide hormone. Localizes to blood microparticle and rough endoplasmic reticulum. Used to study asthma; brain ischemia; disseminated intravascular coagulation; and thrombocytopenia. Biomarker of acute kidney failure; disseminated intravascular coagulation; pancreatitis; pulmonary embolism; and pulmonary emphysema. Human ortholog(s) of this gene implicated in congenital afibrinogenemia; familial visceral amyloidosis; and thrombophilia. Orthologous to human FGA (fibrinogen alpha chain); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
Also known as: Ac1873; Fba5e; Fibrinogen A alpha polypeptide; Fibrinogen A alpha polypeptide see also D2Mit19 and D2Wox16; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; MGC156536
Homo sapiens (human) : FGA (fibrinogen alpha chain)  HGNC  Alliance
Mus musculus (house mouse) : Fga (fibrinogen alpha chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fga (fibrinogen alpha chain)
Pan paniscus (bonobo/pygmy chimpanzee) : FGA (fibrinogen alpha chain)
Canis lupus familiaris (dog) : FGA (fibrinogen alpha chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fga (fibrinogen alpha chain)
Sus scrofa (pig) : FGA (fibrinogen alpha chain)
Chlorocebus sabaeus (African green monkey) : FGA (fibrinogen alpha chain)
Heterocephalus glaber (naked mole-rat) : Fga (fibrinogen alpha chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02181,997,562 - 182,013,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2182,006,242 - 182,013,763 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02201,412,182 - 201,428,346 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,737,640 - 174,753,598 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12174,694,725 - 174,703,904 (+)NCBI
Celera2162,392,064 - 162,408,023 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Fga
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2603
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.