Gene: Fgfr2 (fibroblast growth factor receptor 2) Rattus norvegicus
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Symbol: Fgfr2
Name: fibroblast growth factor receptor 2
Description: Exhibits fibroblast growth factor binding activity and fibroblast growth factor-activated receptor activity; involved in several processes, including cellular response to growth factor stimulus, cellular response to retinoic acid, and endochondral bone growth; localizes to the cell surface, cytoplasm, and nucleus; predicted to colocalize with the collagen-containing extracellular matrix; used to study prostate cancer and retinitis pigmentosa; biomarker of hypospadias; orthologous to human FGFR2 (fibroblast growth factor receptor 2); PARTICIPATES IN fibroblast growth factor signaling pathway; endocytosis pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Orthologs:
Homo sapiens (human) : FGFR2 (fibroblast growth factor receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Fgfr2 (fibroblast growth factor receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr2 (fibroblast growth factor receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR2 (fibroblast growth factor receptor 2)
Canis lupus familiaris (dog) : FGFR2 (fibroblast growth factor receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr2 (fibroblast growth factor receptor 2)
Sus scrofa (pig) : FGFR2 (fibroblast growth factor receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01200,590,951 - 200,696,946 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01207,626,732 - 207,731,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41189,482,975 - 189,589,279 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11189,667,865 - 189,734,790 (-)NCBI
Celera1182,362,666 - 182,467,651 (-)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Fgfr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2611
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.