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Gene: Fgfr2 (fibroblast growth factor receptor 2) Rattus norvegicus
Symbol: Fgfr2
Name: fibroblast growth factor receptor 2
Description: Exhibits fibroblast growth factor binding activity and fibroblast growth factor-activated receptor activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to retinoic acid; and positive regulation of smooth muscle cell proliferation. Localizes to cell surface; cytoplasm; and nucleus. Predicted to colocalize with collagen-containing extracellular matrix. Used to study prostate cancer and retinitis pigmentosa. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in several diseases, including Antley-Bixler syndrome; Beare-Stevenson cutis gyrata syndrome; Jackson-Weiss syndrome; LADD syndrome; and synostosis (multiple). Orthologous to human FGFR2 (fibroblast growth factor receptor 2); PARTICIPATES IN fibroblast growth factor signaling pathway; endocytosis pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Homo sapiens (human) : FGFR2 (fibroblast growth factor receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Fgfr2 (fibroblast growth factor receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr2 (fibroblast growth factor receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR2 (fibroblast growth factor receptor 2)
Canis lupus familiaris (dog) : FGFR2 (fibroblast growth factor receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr2 (fibroblast growth factor receptor 2)
Sus scrofa (pig) : FGFR2 (fibroblast growth factor receptor 2)
Chlorocebus sabaeus (African green monkey) : FGFR2 (fibroblast growth factor receptor 2)
Heterocephalus glaber (naked mole-rat) : Fgfr2 (fibroblast growth factor receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01200,590,951 - 200,696,946 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1200,590,953 - 200,696,928 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01207,626,732 - 207,731,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41189,482,975 - 189,589,279 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11189,667,865 - 189,734,790 (-)NCBI
Celera1182,362,666 - 182,467,651 (-)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Fgfr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2611
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.