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Gene: Fmo1 (flavin containing dimethylaniline monoxygenase 1) Rattus norvegicus
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Symbol: Fmo1
Name: flavin containing dimethylaniline monoxygenase 1
Description: Exhibits N,N-dimethylaniline monooxygenase activity. Involved in response to lipopolysaccharide and response to osmotic stress. Localizes to the intracellular membrane-bounded organelle. Orthologous to human FMO1 (flavin containing dimethylaniline monoxygenase 1); PARTICIPATES IN tamoxifen pharmacodynamics pathway; tamoxifen pharmacokinetics pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dimethylaniline monooxygenase [N-oxide-forming] 1; dimethylaniline oxidase 1; flavin containing monooxygenase 1; Flavin-containing monooxygenase 1; FMO 1; hepatic flavin-containing monooxygenase 1; RFMO1A
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01380,712,885 - 80,745,095 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01385,607,539 - 85,639,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41378,503,770 - 78,536,359 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11378,517,957 - 78,550,547 (-)NCBI
Celera1374,919,415 - 74,951,610 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Fmo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2622
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.