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Gene: Fnta (farnesyltransferase, CAAX box, alpha) Rattus norvegicus
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Symbol: Fnta
Name: farnesyltransferase, CAAX box, alpha
Description: Exhibits protein farnesyltransferase activity. Contributes to several functions, including CAAX-protein geranylgeranyltransferase activity; isoprenoid binding activity; and zinc ion binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cell population proliferation; and regulation of nitric-oxide synthase biosynthetic process. Localizes to the CAAX-protein geranylgeranyltransferase complex and cytoplasm. Orthologous to human FNTA (farnesyltransferase, CAAX box, alpha); INTERACTS WITH (+)-schisandrin B; (-)-perillyl alcohol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAAX farnesyltransferase subunit alpha; Farnesyltransferase subunit alpha; Farnesyltransferase, subunit alpha; FTase-alpha; GGTase-I-alpha; PFAS; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase subunit alpha
Orthologs:
Homo sapiens (human) : FNTA (farnesyltransferase, CAAX box, alpha)  HGNC  Alliance
Mus musculus (house mouse) : Fnta (farnesyltransferase, CAAX box, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fnta (farnesyltransferase, CAAX box, alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : FNTA (farnesyltransferase, CAAX box, alpha)
Canis lupus familiaris (dog) : FNTA (farnesyltransferase, CAAX box, alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fnta (farnesyltransferase, CAAX box, alpha)
Sus scrofa (pig) : FNTA (farnesyltransferase, CAAX box, alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01670,834,957 - 70,854,724 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01670,499,605 - 70,519,062 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,440,340 - 70,458,433 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11670,440,604 - 70,458,698 (+)NCBI
Celera1663,976,260 - 63,994,463 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
RH 3.4 Map16622.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fnta
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2625
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.