Gene: Xrcc6 (X-ray repair cross complementing 6) Rattus norvegicus
Symbol: Xrcc6
Name: X-ray repair cross complementing 6
Description: Contributes to double-stranded DNA binding activity; involved in brain development, cellular hyperosmotic salinity response, and cellular response to X-ray; localizes to the cytoplasm, nucleolus, and protein-containing complex; orthologous to human XRCC6 (X-ray repair cross complementing 6); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G22p1; Ku70; Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa); Kup70; thyroid autoantigen; X-ray repair complementing defective repair in Chinese hamster cells 6; X-ray repair cross-complementing protein 6
Homo sapiens (human) : XRCC6 (X-ray repair cross complementing 6)  HGNC  Alliance
Mus musculus (house mouse) : Xrcc6 (X-ray repair complementing defective repair in Chinese hamster cells 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc6 (X-ray repair cross complementing 6)
Canis lupus familiaris (dog) : XRCC6 (X-ray repair cross complementing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc6 (X-ray repair cross complementing 6)
Sus scrofa (pig) : XRCC6 (X-ray repair cross complementing 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07123,259,881 - 123,280,613 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07123,244,581 - 123,265,278 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,401,944 - 120,422,923 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,436,196 - 120,457,039 (+)NCBI
Celera7109,858,919 - 109,879,605 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Xrcc6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2643
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.