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Gene: Xrcc6 (X-ray repair cross complementing 6) Rattus norvegicus
Symbol: Xrcc6
Name: X-ray repair cross complementing 6
Description: Contributes to double-stranded DNA binding activity. Involved in brain development; cellular hyperosmotic salinity response; and cellular response to X-ray. Localizes to cytoplasm; nucleolus; and protein-containing complex. Orthologous to human XRCC6 (X-ray repair cross complementing 6); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; INTERACTS WITH (+)-alpha-tocopherol; 7,12-dimethyltetraphene; acrylonitrile.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G22p1; Ku70; Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa); Kup70; thyroid autoantigen; X-ray repair complementing defective repair in Chinese hamster cells 6; X-ray repair cross-complementing protein 6
Homo sapiens (human) : XRCC6 (X-ray repair cross complementing 6)  HGNC  Alliance
Mus musculus (house mouse) : Xrcc6 (X-ray repair complementing defective repair in Chinese hamster cells 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc6 (X-ray repair cross complementing 6)
Canis lupus familiaris (dog) : XRCC6 (X-ray repair cross complementing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc6 (X-ray repair cross complementing 6)
Sus scrofa (pig) : XRCC6 (X-ray repair cross complementing 6)
Chlorocebus sabaeus (African green monkey) : XRCC6 (X-ray repair cross complementing 6)
Heterocephalus glaber (naked mole-rat) : Xrcc6 (X-ray repair cross complementing 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07123,259,881 - 123,280,613 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,259,761 - 123,280,612 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,244,581 - 123,265,278 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,401,944 - 120,422,923 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,436,196 - 120,457,039 (+)NCBI
Celera7109,858,919 - 109,879,605 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Xrcc6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2643
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.