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Gene: G6pc1 (glucose-6-phosphatase catalytic subunit 1) Rattus norvegicus
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Symbol: G6pc1
Name: glucose-6-phosphatase catalytic subunit 1
CRRD ID: 2644
Description: Exhibits glucose-6-phosphatase activity. Involved in several processes, including gluconeogenesis; phosphorylated carbohydrate dephosphorylation; and response to resveratrol. Localizes to intracellular membrane-bounded organelle. Used to study type 2 diabetes mellitus. Biomarker of fatty liver disease. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human G6PC (glucose-6-phosphatase catalytic subunit); PARTICIPATES IN altered galactose metabolic pathway; gluconeogenesis pathway; glycogen degradation pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,2-dimethylhydrazine; 1-benzylpiperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G-6-Pase; G6PASE; G6pc; Glucose-6-phosphatase; glucose-6-phosphatase, catalytic; glucose-6-phosphatase, catalytic subunit; MGC93613
Orthologs:
Homo sapiens (human) : G6PC1 (glucose-6-phosphatase catalytic subunit 1)  HGNC  Alliance
Mus musculus (house mouse) : G6pc (glucose-6-phosphatase, catalytic)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pc1 (glucose-6-phosphatase catalytic subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PC1 (glucose-6-phosphatase catalytic subunit 1)
Canis lupus familiaris (dog) : G6PC1 (glucose-6-phosphatase catalytic subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pc1 (glucose-6-phosphatase catalytic subunit 1)
Sus scrofa (pig) : G6PC1 (glucose-6-phosphatase catalytic subunit 1)
Chlorocebus sabaeus (African green monkey) : G6PC1 (glucose-6-phosphatase catalytic subunit 1)
Heterocephalus glaber (naked mole-rat) : G6pc1 (glucose-6-phosphatase catalytic subunit 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01089,286,009 - 89,296,213 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,285,855 - 89,296,213 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,084,064 - 89,094,265 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,393,531 - 90,403,485 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,407,938 - 90,417,855 (+)NCBI
Celera1085,025,492 - 85,036,580 (+)NCBICelera
Cytogenetic Map10q31NCBI
RH 3.4 Map10837.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on G6pc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2644
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.