Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: G6pc (glucose-6-phosphatase, catalytic subunit) Rattus norvegicus
Analyze
Symbol: G6pc
Name: glucose-6-phosphatase, catalytic subunit
Description: Exhibits glucose-6-phosphatase activity. Involved in several processes, including gluconeogenesis; glucose homeostasis; and phosphorylated carbohydrate dephosphorylation. Localizes to the intracellular membrane-bounded organelle. Used to study type 2 diabetes mellitus. Orthologous to human G6PC (glucose-6-phosphatase catalytic subunit); PARTICIPATES IN altered galactose metabolic pathway; gluconeogenesis pathway; glycogen degradation pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,2-dimethylhydrazine; 1-benzylpiperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G-6-Pase; G6PASE; Glucose-6-phosphatase; glucose-6-phosphatase, catalytic; MGC93613
Orthologs:
Homo sapiens (human) : G6PC (glucose-6-phosphatase catalytic subunit)  HGNC  Alliance
Mus musculus (house mouse) : G6pc (glucose-6-phosphatase, catalytic)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pc (glucose-6-phosphatase catalytic subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PC (glucose-6-phosphatase catalytic subunit)
Canis lupus familiaris (dog) : G6PC (glucose-6-phosphatase catalytic subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pc (glucose-6-phosphatase catalytic subunit)
Sus scrofa (pig) : G6PC (glucose-6-phosphatase catalytic subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01089,286,009 - 89,296,213 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01089,084,064 - 89,094,265 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,393,531 - 90,403,485 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,407,938 - 90,417,855 (+)NCBI
Celera1085,025,492 - 85,036,580 (+)NCBICelera
Cytogenetic Map10q31NCBI
RH 3.4 Map10837.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on G6pc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2644
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.