Gene: G6pd (glucose-6-phosphate dehydrogenase) Rattus norvegicus
Analyze
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Description: Exhibits NADP binding activity, glucose binding activity, and glucose-6-phosphate dehydrogenase activity; involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development, negative regulation of reactive oxygen species metabolic process, and pentose-phosphate shunt, oxidative branch; localizes to the cytosol and nucleus; used to study cataract and transient cerebral ischemia; biomarker of several diseases, including artery disease (multiple), cholestasis, congenital hypothyroidism, hepatic encephalopathy, and hepatocellular carcinoma; orthologous to human G6PD (glucose-6-phosphate dehydrogenase); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH (R)-noradrenaline; (S)-naringenin; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G6pdx; glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase X-linked
Orthologs:
Homo sapiens (human) : G6PD (glucose-6-phosphate dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : G6pdx (glucose-6-phosphate dehydrogenase X-linked)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pd (glucose-6-phosphate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PD (glucose-6-phosphate dehydrogenase)
Canis lupus familiaris (dog) : G6PD (glucose-6-phosphate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pd (glucose-6-phosphate dehydrogenase)
Sus scrofa (pig) : G6PD (glucose-6-phosphate dehydrogenase)
more info ...
Related Pseudogenes: LOC366715  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X156,274,800 - 156,293,935 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,015,532 - 152,034,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,186,450 - 160,192,316 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1135,676,941 - 135,696,556 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on G6pd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2645
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.