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Gene: Ggt1 (gamma-glutamyltransferase 1) Rattus norvegicus
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Symbol: Ggt1
Name: gamma-glutamyltransferase 1
CRRD ID: 2683
Description: Exhibits transferase activity, transferring amino-acyl groups. Involved in several processes, including liver development; peptide modification; and response to estradiol. Localizes to extracellular space. Biomarker of alcohol dependence. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (R)-lipoic acid; (S)-nicotine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Gamma glutamyl-transferase 1; gamma-glutamyl transpeptidase; gamma-glutamyltransferase; gamma-glutamyltranspeptidase; gamma-glutamyltranspeptidase 1; GGLUT; Ggt; GGT 1; Ggtp; glutathione hydrolase 1; glutathione hydrolase 1 proenzyme; leukotriene-C4 hydrolase; RATGGLUT
Orthologs:
Homo sapiens (human) : GGT1 (gamma-glutamyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ggt1 (gamma-glutamyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ggt1 (gamma-glutamyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GGT1 (gamma-glutamyltransferase 1)
Canis lupus familiaris (dog) : GGT1 (gamma-glutamyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ggt1 (gamma-glutamyltransferase 1)
Chlorocebus sabaeus (African green monkey) : GGT1 (gamma-glutamyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Ggt1 (gamma-glutamyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02014,019,723 - 14,045,781 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,019,723 - 14,025,068 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,209,337 - 16,231,303 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2014,560,916 - 14,581,414 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ggt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2683
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.