Gene: Gh1 (growth hormone 1) Rattus norvegicus
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Symbol: Gh1
Name: growth hormone 1
Description: Exhibits hormone activity; involved in several processes, including cellular response to alkaline pH, cellular response to thyroid hormone stimulus, and generation of neurons; localizes to several cellular components, including the collagen-containing extracellular matrix, cytoplasm, and extracellular space; used to study type 1 diabetes mellitus; biomarker of congenital hypothyroidism, osteoporosis, and type 2 diabetes mellitus; orthologous to several human genes including GH1 (growth hormone 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gh; Ghb1; growth hormone b1; RNGHGP; somatotropin
Orthologs:
Homo sapiens (human) : GH1 (growth hormone 1)  HGNC  Alliance
Mus musculus (house mouse) : Gh (growth hormone)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100971425 (somatotropin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969021 (somatotropin)
more info ...
Allele / Splice: Gh1sdr  
Genetic Models: SDR/Slc
Is Marker For: QTLs:   Bp1   Cia5   Bp134  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01094,486,204 - 94,488,181 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,237,414 - 94,239,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,692,240 - 95,694,117 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11095,708,476 - 95,710,261 (-)NCBI
Celera1089,903,834 - 89,905,811 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2686
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.