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Gene: Gja4 (gap junction protein, alpha 4) Rattus norvegicus
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Symbol: Gja4
Name: gap junction protein, alpha 4
Description: Involved in several processes, including cell-cell signaling; endothelium development; and response to pain. Localizes to the connexin complex. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human GJA4 (gap junction protein alpha 4); PARTICIPATES IN connexin signaling pathway; INTERACTS WITH (S)-nicotine; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: connexin-37; cx37; CXN37; gap junction alpha-4 protein; gap junction membrane channel protein alpha 4; Gap junction membrane channel protein alpha 4 (connexin 37); Gap junction membrane channel, protein alpha 4 (connexin 37)
Orthologs:
Homo sapiens (human) : GJA4 (gap junction protein alpha 4)  HGNC  Alliance
Mus musculus (house mouse) : Gja4 (gap junction protein, alpha 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gja4 (gap junction protein alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GJA4 (gap junction protein alpha 4)
Canis lupus familiaris (dog) : GJA4 (gap junction protein alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gja4 (gap junction protein alpha 4)
Sus scrofa (pig) : GJA4 (gap junction protein alpha 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05145,374,688 - 145,377,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05149,142,702 - 149,145,235 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45146,755,061 - 146,757,594 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15146,765,101 - 146,767,633 (-)NCBI
Celera5138,127,254 - 138,129,787 (-)NCBICelera
Cytogenetic Map5q36NCBI
RH 3.4 Map5934.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gja4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2691
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.