Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gja4 (gap junction protein, alpha 4) Rattus norvegicus
Symbol: Gja4
Name: gap junction protein, alpha 4
CRRD ID: 2691
Description: Predicted to have gap junction channel activity. Involved in several processes, including calcium ion transport; endothelium development; and response to pain. Localizes to connexin complex. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human GJA4 (gap junction protein alpha 4); PARTICIPATES IN connexin signaling pathway; INTERACTS WITH (S)-nicotine; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: connexin h1; connexin-37; cx37; CXN37; Cxnh1; gap junction alpha-4 protein; gap junction membrane channel protein alpha 4; Gap junction membrane channel protein alpha 4 (connexin 37); Gap junction membrane channel, protein alpha 4 (connexin 37)
Homo sapiens (human) : GJA4 (gap junction protein alpha 4)  HGNC  Alliance
Mus musculus (house mouse) : Gja4 (gap junction protein, alpha 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gja4 (gap junction protein alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GJA4 (gap junction protein alpha 4)
Canis lupus familiaris (dog) : GJA4 (gap junction protein alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gja4 (gap junction protein alpha 4)
Sus scrofa (pig) : GJA4 (gap junction protein alpha 4)
Chlorocebus sabaeus (African green monkey) : GJA4 (gap junction protein alpha 4)
Heterocephalus glaber (naked mole-rat) : Gja4 (gap junction protein alpha 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05145,374,688 - 145,377,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5145,374,690 - 145,377,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05149,142,702 - 149,145,235 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45146,755,061 - 146,757,594 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15146,765,101 - 146,767,633 (-)NCBI
Celera5138,127,254 - 138,129,787 (-)NCBICelera
Cytogenetic Map5q36NCBI
RH 3.4 Map5934.8RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gja4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2691
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.