Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Glo1 (glyoxalase 1) Rattus norvegicus
Analyze
Symbol: Glo1
Name: glyoxalase 1
Description: Exhibits lactoylglutathione lyase activity. Involved in carbohydrate metabolic process; glutathione metabolic process; and methylglyoxal metabolic process. Predicted to localize to cytosol; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder; diabetic retinopathy; end stage renal disease; type 2 diabetes mellitus; and vascular disease. Orthologous to human GLO1 (glyoxalase I); PARTICIPATES IN glyoxalase metabolic pathway; Leigh disease pathway; primary hyperoxaluria type 2 pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; aminoguanidine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aldoketomutase; glx I; glyoxalase I; glyoxylase 1; ketone-aldehyde mutase; lactoylglutathione lyase; methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
Orthologs:
Homo sapiens (human) : GLO1 (glyoxalase I)  HGNC  Alliance
Mus musculus (house mouse) : Glo1 (glyoxalase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glo1 (glyoxalase I)
Pan paniscus (bonobo/pygmy chimpanzee) : GLO1 (glyoxalase I)
Canis lupus familiaris (dog) : GLO1 (glyoxalase I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glo1 (glyoxalase I)
Sus scrofa (pig) : GLO1 (glyoxalase I)
Chlorocebus sabaeus (African green monkey) : GLO1 (glyoxalase I)
Heterocephalus glaber (naked mole-rat) : Glo1 (glyoxalase I)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0209,273,589 - 9,291,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl209,273,594 - 9,291,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02011,461,655 - 11,479,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4208,900,984 - 8,919,001 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1208,901,210 - 8,919,228 (-)NCBI
Celera2010,191,302 - 10,209,289 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Glo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2702
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.