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Gene: Glra1 (glycine receptor, alpha 1) Rattus norvegicus
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Symbol: Glra1
Name: glycine receptor, alpha 1
CRRD ID: 2704
Description: Exhibits extracellularly glycine-gated chloride channel activity; glycine binding activity; and identical protein binding activity. Predicted to contribute to chloride channel activity. Involved in chloride transport and glycinergic synaptic transmission. Localizes to several cellular components, including calyx of Held; glycinergic synapse; and integral component of synaptic membrane. Human ortholog(s) of this gene implicated in hyperekplexia 1. Orthologous to human GLRA1 (glycine receptor alpha 1); PARTICIPATES IN Inhibitory synaptic transmission pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glycine receptor 48 kDa subunit; glycine receptor strychnine-binding subunit; glycine receptor subunit alpha-1; glycine receptor, alpha 1 subunit; GLYRA1
Orthologs:
Homo sapiens (human) : GLRA1 (glycine receptor alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Glra1 (glycine receptor, alpha 1 subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glra1 (glycine receptor alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GLRA1 (glycine receptor alpha 1)
Canis lupus familiaris (dog) : GLRA1 (glycine receptor alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glra1 (glycine receptor alpha 1)
Sus scrofa (pig) : GLRA1 (glycine receptor alpha 1)
Chlorocebus sabaeus (African green monkey) : GLRA1 (glycine receptor alpha 1)
Heterocephalus glaber (naked mole-rat) : Glra1 (glycine receptor alpha 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01040,851,955 - 40,954,364 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,855,559 - 40,953,651 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01040,687,069 - 40,785,100 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,922,867 - 41,021,767 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11040,936,489 - 41,035,390 (-)NCBI
Celera1038,958,969 - 39,055,009 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Glra1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2704
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.