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Gene: Glud1 (glutamate dehydrogenase 1) Rattus norvegicus
Symbol: Glud1
Name: glutamate dehydrogenase 1
Description: Exhibits enzyme binding activity and glutamate dehydrogenase (NAD+) activity. Involved in cerebellum development; long-term memory; and response to aluminum ion. Localizes to mitochondrion. Biomarker of brain disease (multiple) and fascioliasis. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; AGAT deficiency pathway; arginine and proline metabolic pathway; INTERACTS WITH 1,1,2-trichloroethane; 1,2-dichlorobenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ac2-281; GDH 1; Gdh1; Glud; Gludeha; glutamate dehydrogenase; glutamate dehydrogenase 1, mitochondrial; memory related gene 2; memory-related gene 2; memory-related protein 2; MGC93608; MRG-2; RNGLUDEHA
Homo sapiens (human) : GLUD1 (glutamate dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Glud1 (glutamate dehydrogenase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glud1 (glutamate dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GLUD1 (glutamate dehydrogenase 1)
Canis lupus familiaris (dog) : GLUD1 (glutamate dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glud1 (glutamate dehydrogenase 1)
Sus scrofa (pig) : GLUD1 (glutamate dehydrogenase 1)
Heterocephalus glaber (naked mole-rat) : Glud1 (glutamate dehydrogenase 1)
more info ...
Is Marker For: QTLs:   BpQTLcluster13  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01610,661,486 - 10,695,557 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,662,021 - 10,695,557 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,980,352 - 9,014,005 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,965,718 - 9,999,254 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1169,965,715 - 9,999,248 (+)NCBI
Celera165,542,860 - 5,576,454 (-)NCBICelera
Cytogenetic Map16p15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Glud1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2708
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.