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Gene: Gnal (G protein subunit alpha L) Rattus norvegicus
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Symbol: Gnal
Name: G protein subunit alpha L
Description: Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in several processes, including activation of adenylate cyclase activity; adenylate cyclase-activating dopamine receptor signaling pathway; and response to caffeine. Predicted to localize to the heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L); PARTICIPATES IN dopamine signaling pathway via D1 family of receptors; endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate cyclase-stimulating G alpha protein, olfactory type; Golf; guanine nucleotide binding protein, alpha activating activity polypeptide, olfactory type; guanine nucleotide binding protein, alpha stimulating, olfactory type; guanine nucleotide-binding protein G(olf) subunit alpha; guanine nucleotide-binding protein G(olf), alpha subunit; LOC361343; Olf; Olf-alpha protein (olfactory neuron-specific G protein); RGD1305940; similar to RIKEN cDNA 9630020G10 gene
Orthologs:
Homo sapiens (human) : GNAL (G protein subunit alpha L)  HGNC  Alliance
Mus musculus (house mouse) : Gnal (guanine nucleotide binding protein, alpha stimulating, olfactory type)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnal (G protein subunit alpha L)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAL (G protein subunit alpha L)
Canis lupus familiaris (dog) : GNAL (G protein subunit alpha L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnal (G protein subunit alpha L)
Sus scrofa (pig) : GNAL (G protein subunit alpha L)
more info ...
Is Marker For: Strains:   BB.SHR-(Gnal-D18Mit9)/K  
QTLs:   Iddm4   Bp48   Iddm15   Sprol1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01862,805,406 - 62,946,133 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01861,991,738 - 62,131,420 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41863,595,606 - 63,735,803 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11863,668,806 - 63,809,004 (+)NCBI
Celera1858,730,137 - 58,870,361 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gnal
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2715
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.