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Gene: Grik5 (glutamate ionotropic receptor kainate type subunit 5) Rattus norvegicus
Symbol: Grik5
Name: glutamate ionotropic receptor kainate type subunit 5
Description: Exhibits identical protein binding activity; kainate selective glutamate receptor activity; and protein domain specific binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of neuron apoptotic process; and protein retention in ER lumen. Localizes to several cellular components, including glutamatergic synapse; integral component of plasma membrane; and perikaryon. Used to study visual epilepsy. Biomarker of temporal lobe epilepsy. Orthologous to human GRIK5 (glutamate ionotropic receptor kainate type subunit 5); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GluK5; glutamate receptor ionotropic, kainate 5; glutamate receptor KA-2; glutamate receptor KA2; glutamate receptor, ionotropic kainate 5; glutamate receptor, ionotropic, kainate 5; iGlu5; KA2
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0181,885,516 - 81,946,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,885,521 - 81,946,714 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,137,805 - 83,207,039 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,313,801 - 80,384,390 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,391,911 - 80,462,398 (-)NCBI
Celera175,051,832 - 75,112,171 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Grik5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2735
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.