Gene: Grm1 (glutamate metabotropic receptor 1) Rattus norvegicus
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Symbol: Grm1
Name: glutamate metabotropic receptor 1
Description: Exhibits G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential, estrogen receptor binding activity, and identical protein binding activity; involved in several processes, including G protein-coupled glutamate receptor signaling pathway, calcium-mediated signaling, and chemical synaptic transmission; localizes to the glutamatergic synapse, neuron projection, and synaptic membrane; biomarker of temporal lobe epilepsy; orthologous to human GRM1 (glutamate metabotropic receptor 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; glutamate signaling pathway; Huntington's disease pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-3,5-dihydroxyphenylglycine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; glutamate receptor, metabotropic 1; Gprc1a; metabotropic glutamate receptor 1; mGluR1
Orthologs:
Homo sapiens (human) : GRM1 (glutamate metabotropic receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Grm1 (glutamate receptor, metabotropic 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm1 (glutamate metabotropic receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM1 (glutamate metabotropic receptor 1)
Canis lupus familiaris (dog) : GRM1 (glutamate metabotropic receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm1 (glutamate metabotropic receptor 1)
Sus scrofa (pig) : GRM1 (glutamate metabotropic receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.014,753,141 - 5,165,859 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.016,815,959 - 6,818,380 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.016,413,420 - 6,685,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415,318,617 - 5,744,593 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115,318,616 - 5,744,590 (-)NCBI
Celera13,589,875 - 3,976,624 (-)NCBICelera
Cytogenetic Map1p13NCBI
SHRSP x BN Map15.6799RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Grm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2742
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.