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Gene: Grm4 (glutamate metabotropic receptor 4) Rattus norvegicus
Symbol: Grm4
Name: glutamate metabotropic receptor 4
Description: Exhibits calcium-dependent protein binding activity and calmodulin binding activity. Predicted to be involved in several processes, including activation of MAPK activity; adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; and modulation of chemical synaptic transmission. Localizes to dendritic shaft; presynaptic active zone membrane; and terminal bouton. Orthologous to human GRM4 (glutamate metabotropic receptor 4); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; benzo[a]pyrene.
Type: protein-coding
Also known as: glutamate receptor, metabotropic 4; metabotropic glutamate receptor 4; mGluR4
Homo sapiens (human) : GRM4 (glutamate metabotropic receptor 4)  HGNC  Alliance
Mus musculus (house mouse) : Grm4 (glutamate receptor, metabotropic 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm4 (glutamate metabotropic receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM4 (glutamate metabotropic receptor 4)
Canis lupus familiaris (dog) : GRM4 (glutamate metabotropic receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm4 (glutamate metabotropic receptor 4)
Sus scrofa (pig) : GRM4 (glutamate metabotropic receptor 4)
Heterocephalus glaber (naked mole-rat) : Grm4 (glutamate metabotropic receptor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: There is an assembly problem in the Rnor_6.0 reference genome assembly, and therefore, the 5' end of this gene was annotated on NW_007906049.1 and the 3' end was annotated on NW_007906047.1 in NCBI's Rattus norvegicus Annotation Release 105. [17 Jun 2015]; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0206,745,682 - 6,791,521 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,745,682 - 6,791,519 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0208,986,551 - 9,064,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,627,733 - 5,727,274 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,627,959 - 5,727,501 (-)NCBI
Celera207,048,565 - 7,156,973 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Grm4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2745
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.