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Gene: Gsta2 (glutathione S-transferase alpha 2) Rattus norvegicus
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Symbol: Gsta2
Name: glutathione S-transferase alpha 2
Description: Exhibits several functions, including glutathione binding activity; glutathione transferase activity; and protein homodimerization activity. Involved in aging and xenobiotic catabolic process. Localizes to the cytosol and nuclear outer membrane. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Orthologous to several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 13-hydroperoxyoctadecadienoate peroxidase; androst-5-ene-3,17-dione isomerase; glutathione S-transferase A2; glutathione S-transferase alpha-1; glutathione S-transferase Ya subunit; glutathione S-transferase Ya-1; glutathione S-transferase, alpha 2; Glutathione-S-transferase alpha type (Yc?); Glutathione-S-transferase, alpha type (Yc?); glutathione-S-transferase, alpha type2; GST 1-1; GST 1a-1a; GST A1-1; GST B; GST Ya1; Gsta1; ligandin
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0885,640,081 - 85,645,621 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0885,197,052 - 85,202,588 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,299,249 - 83,312,958 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1883,318,303 - 83,332,012 (-)NCBI
Celera878,931,925 - 78,944,156 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gsta2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2754
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.