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Gene: Gstp1 (glutathione S-transferase pi 1) Rattus norvegicus
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Symbol: Gstp1
Name: glutathione S-transferase pi 1
Description: Exhibits several functions, including glutathione binding activity; glutathione transferase activity; and protein kinase binding activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to epidermal growth factor stimulus; and cellular response to hormone stimulus. Localizes to cytosol; nucleus; and plasma membrane. Biomarker of cholestasis; pre-malignant neoplasm; prostate carcinoma in situ; prostatic hypertrophy; and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including brain disease (multiple); carcinoma (multiple); hematologic cancer (multiple); neurodegenerative disease (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (glutathione S-transferase pi 1); PARTICIPATES IN glutathione conjugation pathway; paracetamol pharmacokinetics pathway; glutathione metabolic pathway; INTERACTS WITH (3,4-dihydroxyphenyl)acetic acid; (R)-lipoic acid; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chain 7; glutathione S-transferase P; glutathione S-transferase pi 2; glutathione S-transferase, pi 2; Glutathione-S-transferase placental enzyme pi type; glutathione-S-transferase, pi 1; Glutathione-S-transferase, placental enzyme pi type; GST 7-7; GST class-pi; GST-P; Gst3; Gstp; Gstp2; MGC72668; MGC72669
Orthologs:
Homo sapiens (human) : GSTP1 (glutathione S-transferase pi 1)  HGNC  Alliance
Mus musculus (house mouse) : Gstp1 (glutathione S-transferase, pi 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gstp1 (glutathione S-transferase pi 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GSTP1 (glutathione S-transferase pi 1)
Canis lupus familiaris (dog) : GSTP1 (glutathione S-transferase pi 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gstp1 (glutathione S-transferase pi 1)
Sus scrofa (pig) : LOC100739163 (glutathione S-transferase P-like)
Chlorocebus sabaeus (African green monkey) : GSTP1 (glutathione S-transferase pi 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01219,291,679 - 219,294,147 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,291,679 - 219,294,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,162,330 - 226,164,798 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,627,398 - 206,629,866 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11206,780,853 - 206,783,288 (-)NCBI
Celera1198,882,807 - 198,885,275 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gstp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2758
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.