Gene: Has2 (hyaluronan synthase 2) Rattus norvegicus
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Symbol: Has2
Name: hyaluronan synthase 2
Description: Exhibits hyaluronan synthase activity; involved in several processes, including estrous cycle, hyaluronan biosynthetic process, and positive regulation of cell migration; predicted to localize to the cytoplasm, integral component of plasma membrane, and plasma membrane raft; biomarker of diabetes insipidus, middle cerebral artery infarction, and pulmonary hypertension; orthologous to human HAS2 (hyaluronan synthase 2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HA synthase 2; hyaluronate synthase 2; hyaluronic acid synthase 2
Orthologs:
Homo sapiens (human) : HAS2 (hyaluronan synthase 2)  HGNC  Alliance
Mus musculus (house mouse) : Has2 (hyaluronan synthase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Has2 (hyaluronan synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HAS2 (hyaluronan synthase 2)
Canis lupus familiaris (dog) : HAS2 (hyaluronan synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Has2 (hyaluronan synthase 2)
Sus scrofa (pig) : SHAS2 (hyaluronan synthase 2)
more info ...
Allele / Splice: Has2m1Mcwi  
Genetic Models: BN-Has2m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0796,438,046 - 96,464,049 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0797,055,458 - 97,081,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4793,230,135 - 93,256,139 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1793,264,364 - 93,290,369 (-)NCBI
Celera784,901,996 - 84,927,998 (-)NCBICelera
Cytogenetic Map7q33NCBI
RH 3.4 Map7607.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Has2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2781
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.