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Gene: Hba-a1 (hemoglobin alpha, adult chain 1) Rattus norvegicus
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Symbol: Hba-a1
Name: hemoglobin alpha, adult chain 1
Description: Exhibits amyloid-beta binding activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Involved in negative regulation of blood pressure and regulation of sensory perception of pain. Localizes to synapse. Used to study alpha thalassemia. Biomarker of Alzheimer's disease; PARTICIPATES IN malaria pathway; sleeping sickness pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1/2-globin; Hba-a2; Hba1; HBAM; hemoglobin alpha 1 chain; hemoglobin alpha, adult chain 2; hemoglobin alpha-1/2 chain; hemoglobin subunit alpha-1/2; hemoglobin, alpha 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01015,602,794 - 15,603,649 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,602,794 - 15,603,649 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,497,889 - 15,498,744 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,584,360 - 15,585,215 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,585,407 - 15,586,263 (-)NCBI
Celera1015,004,857 - 15,005,712 (-)NCBICelera
Cytogenetic Map10q12NCBI
RH 3.4 Map10153.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hba-a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2782
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.