Gene: Hk1 (hexokinase 1) Rattus norvegicus
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Symbol: Hk1
Name: hexokinase 1
Description: Exhibits several functions, including ATP binding activity, glucose binding activity, and transferase activity, transferring phosphorus-containing groups; involved in several processes, including negative regulation of apoptotic process, phosphorylation, and regulation of anion channel activity; localizes to the caveola, cytoplasm, and protein-containing complex; used to study obesity and urinary bladder cancer; biomarker of colorectal cancer and pulmonary hypertension; orthologous to human HK1 (hexokinase 1); PARTICIPATES IN glycolysis pathway; amino sugar metabolic pathway; french type sialuria pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: brain form hexokinase; hexokin; hexokinase type I; hexokinase-1; HK I; HKI; rathexokin
Orthologs:
Homo sapiens (human) : HK1 (hexokinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Hk1 (hexokinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hk1 (hexokinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HK1 (hexokinase 1)
Canis lupus familiaris (dog) : HK1 (hexokinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hk1 (hexokinase 1)
Sus scrofa (pig) : HK1 (hexokinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02031,911,460 - 31,979,780 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02033,703,472 - 33,770,598 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2031,652,769 - 31,721,279 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2796
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.