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Gene: Hmox1 (heme oxygenase 1) Rattus norvegicus
Symbol: Hmox1
Name: heme oxygenase 1
Description: Exhibits several functions, including heme binding activity; heme oxygenase (decyclizing) activity; and phospholipase D activity. Involved in several processes, including intracellular signal transduction; negative regulation of apoptotic process; and negative regulation of immune response. Localizes to several cellular components, including caveola; endoplasmic reticulum; and nucleolus. Used to study several diseases, including artery disease (multiple); cerebrovascular disease (multiple); hepatic vascular disease (multiple); limb ischemia; and sciatic neuropathy. Biomarker of several diseases, including Sjogren's syndrome; artery disease (multiple); brain disease (multiple); liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and type 2 diabetes mellitus. Orthologous to human HMOX1 (heme oxygenase 1); PARTICIPATES IN heme degradation pathway; hypertension pathway; oxidative stress response pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (R)-lipoic acid.
Type: protein-coding
Also known as: heme oxygenas; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; Heox; HEOXG; Hmox; Ho-1; Ho1; hsp32
Homo sapiens (human) : HMOX1 (heme oxygenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Hmox1 (heme oxygenase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmox1 (heme oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HMOX1 (heme oxygenase 1)
Canis lupus familiaris (dog) : HMOX1 (heme oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmox1 (heme oxygenase 1)
Sus scrofa (pig) : HMOX1 (heme oxygenase 1)
Chlorocebus sabaeus (African green monkey) : HMOX1 (heme oxygenase 1)
Heterocephalus glaber (naked mole-rat) : Hmox1 (heme oxygenase 1)
more info ...
Is Marker For: Strains:   SS/Jr  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01914,508,634 - 14,515,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1914,508,616 - 14,515,456 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01925,622,556 - 25,629,377 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41913,963,139 - 13,969,960 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11913,967,964 - 13,974,784 (+)NCBI
Celera1913,334,259 - 13,341,080 (+)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)