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Gene: Hprt1 (hypoxanthine phosphoribosyltransferase 1) Rattus norvegicus
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Symbol: Hprt1
Name: hypoxanthine phosphoribosyltransferase 1
Description: Exhibits hypoxanthine phosphoribosyltransferase activity. Involved in several processes, including cellular response to insulin stimulus; hypoxanthine metabolic process; and spermatogenesis. Predicted to localize to the cytosol. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Lesch-Nyhan syndrome. Orthologous to human HPRT1 (hypoxanthine phosphoribosyltransferase 1); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH (RS)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HGPRT; Hgprtase; Hprt; hypoxanthine guanine phosphoribosyl transferase; hypoxanthine guanine phosphoribosyl transferase 1; Hypoxanthine phosphoribosyl transferase; hypoxanthine-guanine phosphoribosyltransferase; MGC112554
Orthologs:
Homo sapiens (human) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Hprt (hypoxanthine guanine phosphoribosyl transferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Canis lupus familiaris (dog) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
Sus scrofa (pig) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X158,196,640 - 158,228,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X153,249,874 - 153,281,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X152,821,947 - 152,854,198 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X139,929,647 - 139,961,616 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X140,003,079 - 140,035,048 (+)NCBI
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hprt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2826
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.