Gene: Hspa1b (heat shock protein family A (Hsp70) member 1B) Rattus norvegicus
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Symbol: Hspa1b
Name: heat shock protein family A (Hsp70) member 1B
Description: Exhibits NF-kappaB binding activity and protease binding activity; involved in several processes, including defense response, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, and negative regulation of vasoconstriction; localizes to several cellular components, including the apical plasma membrane, basolateral plasma membrane, and cytosol; predicted to colocalize with the COP9 signalosome and ubiquitin ligase complex; orthologous to several human genes including HSPA1B (heat shock protein family A (Hsp70) member 1B); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-alpha-tocopherol; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; Heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; heat shock 70kD protein 1A; heat shock 70kD protein 1B; heat shock protein 1B; Heat shock protein 70-1; heat shock protein family A member 1B; Hsp70-1; HSP70-1/HSP70-2; Hsp70-2; HSP70.1; HSP70.1/2; HSP70.1/HSP70.2; HSP70.2; HSP72; Hspa1; Hspa1a; Hspa2
Orthologs:
Homo sapiens (human) : HSPA1B (heat shock protein family A (Hsp70) member 1B)  HGNC  Alliance
Mus musculus (house mouse) : Hspa1b (heat shock protein 1B)  MGI  Alliance
Canis lupus familiaris (dog) : HSP70 (heat shock protein 70)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa1b (heat shock protein family A (Hsp70) member 1B)
more info ...
Is Marker For: Strains:   SHR-Hspa1em1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,877,638 - 4,880,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,029,038 - 7,033,025 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0204,802,576 - 4,804,849 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,955,274 - 3,957,748 (+)NCBIRGSC3.4rn4RGSC3.4
Celera204,167,705 - 4,171,749 (-)NCBICelera
Cytogenetic Map20p12NCBI
RH 3.4 Map20 RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hspa1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2840
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.