Gene: Hspa5 (heat shock protein family A (Hsp70) member 5) Rattus norvegicus
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Symbol: Hspa5
Name: heat shock protein family A (Hsp70) member 5
Description: Exhibits misfolded protein binding activity and unfolded protein binding activity; involved in several processes, including cellular response to antibiotic, cellular response to metal ion, and generation of neurons; localizes to the membrane, mitochondrion, and smooth endoplasmic reticulum; predicted to colocalize with the COP9 signalosome; biomarker of fatty liver disease, post-traumatic stress disorder, transient cerebral ischemia, ureteral obstruction, and visual epilepsy; orthologous to human HSPA5 (heat shock protein family A (Hsp70) member 5); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 78 kDa glucose-regulated protein; BIP; endoplasmic reticulum chaperone BiP; GRP 78; GRP-78; GRP78; heat shock 70 kDa protein 5; Heat shock 70kD protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A member 5; HSP70 family protein 5; immunoglobulin heavy chain-binding protein; steroidogenesis-activator polypeptide
Orthologs:
Homo sapiens (human) : HSPA5 (heat shock protein family A (Hsp70) member 5)  HGNC  Alliance
Mus musculus (house mouse) : Hspa5 (heat shock protein 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspa5 (heat shock protein family A (Hsp70) member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPA5 (heat shock protein family A (Hsp70) member 5)
Canis lupus familiaris (dog) : HSPA5 (heat shock protein family A (Hsp70) member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa5 (heat shock protein family A (Hsp70) member 5)
Sus scrofa (pig) : HSPA5 (heat shock protein family A (Hsp70) member 5)
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Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0313,838,304 - 13,842,763 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0319,157,874 - 19,162,333 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4313,783,825 - 13,788,022 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1313,680,196 - 13,684,394 (+)NCBI
Celera312,776,654 - 12,781,113 (+)NCBICelera
Cytogenetic Map3p11NCBI
RH 3.4 Map3151.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History