Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Htr4 (5-hydroxytryptamine receptor 4) Rattus norvegicus
Analyze
Symbol: Htr4
Name: 5-hydroxytryptamine receptor 4
Description: Exhibits G protein-coupled serotonin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and gamma-aminobutyric acid signaling pathway. Predicted to localize to the cytoplasm; dendrite; and integral component of plasma membrane. Orthologous to human HTR4 (5-hydroxytryptamine receptor 4); PARTICIPATES IN serotonin signaling pathway via receptors engaging G alphas protein family; calcium/calcium-mediated signaling pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5 hydroxytryptamine ( serotonin) receptor 4; 5-HT-4; 5-HT4 receptor (two splicing variants L; 5-HT4 receptor (two splicing variants L and S); 5-hydroxytryptamine (serotonin) receptor 4; 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled; serotonin receptor 4
Orthologs:
Homo sapiens (human) : HTR4 (5-hydroxytryptamine receptor 4)  HGNC  Alliance
Mus musculus (house mouse) : Htr4 (5 hydroxytryptamine (serotonin) receptor 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr4 (5-hydroxytryptamine receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR4 (5-hydroxytryptamine receptor 4)
Canis lupus familiaris (dog) : HTR4 (5-hydroxytryptamine receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr4 (5-hydroxytryptamine receptor 4)
Sus scrofa (pig) : HTR4 (5-hydroxytryptamine receptor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01857,637,013 - 57,820,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01856,863,669 - 57,046,345 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41858,417,163 - 58,468,888 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11858,489,392 - 58,542,436 (+)NCBI
Celera1853,929,187 - 54,054,080 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Htr4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2850
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.