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Gene: Id1 (inhibitor of DNA binding 1, HLH protein) Rattus norvegicus
Symbol: Id1
Name: inhibitor of DNA binding 1, HLH protein
CRRD ID: 2858
Description: Exhibits several functions, including identical protein binding activity; proteasome binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to organonitrogen compound; and nervous system development. Localizes to centrosome and nucleus. Used to study pulmonary hypertension. Biomarker of cholestasis. Orthologous to human ID1 (inhibitor of DNA binding 1, HLH protein); PARTICIPATES IN interleukin-3 signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-binding protein inhibitor ID-1; ID125A; Idb1; inhibitor of differentiation 1; inhibitor of DNA binding 1; Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation); inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation); MGC156482
Homo sapiens (human) : ID1 (inhibitor of DNA binding 1, HLH protein)  HGNC  Alliance
Mus musculus (house mouse) : Id1 (inhibitor of DNA binding 1, HLH protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Id1 (inhibitor of DNA binding 1, HLH protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ID1 (inhibitor of DNA binding 1, HLH protein)
Canis lupus familiaris (dog) : ID1 (inhibitor of DNA binding 1, HLH protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Id1 (inhibitor of DNA binding 1, HLH protein)
Sus scrofa (pig) : ID1 (inhibitor of DNA binding 1, HLH protein)
Chlorocebus sabaeus (African green monkey) : ID1 (inhibitor of DNA binding 1, HLH protein)
Heterocephalus glaber (naked mole-rat) : Id1 (inhibitor of DNA binding 1, HLH protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03148,214,623 - 148,216,715 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,215,540 - 148,216,718 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,619,728 - 154,621,190 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,086,162 - 143,087,289 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13142,991,791 - 142,992,906 (+)NCBI
Celera3139,960,608 - 139,961,735 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Id1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2858
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.