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Gene: Id2 (inhibitor of DNA binding 2) Rattus norvegicus
Symbol: Id2
Name: inhibitor of DNA binding 2
Description: Predicted to have ion channel binding activity. Involved in several processes, including cellular response to follicle-stimulating hormone stimulus; negative regulation of transcription by RNA polymerase II; and positive regulation of cell population proliferation. Localizes to chromatin; cytosol; and nucleus. Orthologous to human ID2 (inhibitor of DNA binding 2); PARTICIPATES IN hypoxia inducible factor pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: Ac2-300; DNA-binding protein inhibitor ID-2; inhibitor of differentiation 2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; inhibitor of DNA binding 2, HLH protein; MGC105494
Homo sapiens (human) : ID2 (inhibitor of DNA binding 2)  HGNC  Alliance
Mus musculus (house mouse) : Id2 (inhibitor of DNA binding 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Id2 (inhibitor of DNA binding 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ID2 (inhibitor of DNA binding 2)
Canis lupus familiaris (dog) : ID2 (inhibitor of DNA binding 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Id2 (inhibitor of DNA binding 2)
Sus scrofa (pig) : ID2 (inhibitor of DNA binding 2)
Chlorocebus sabaeus (African green monkey) : ID2 (inhibitor of DNA binding 2)
Heterocephalus glaber (naked mole-rat) : Id2 (inhibitor of DNA binding 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0644,360,077 - 44,361,908 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl644,348,501 - 44,363,915 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0653,084,391 - 53,086,222 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4642,781,476 - 42,783,307 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1642,784,059 - 42,786,427 (-)NCBI
Celera641,019,266 - 41,021,097 (-)NCBICelera
Cytogenetic Map6q16NCBI
RH 3.4 Map6240.21RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Id2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2859
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.