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Gene: Igfbp1 (insulin-like growth factor binding protein 1) Rattus norvegicus
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Symbol: Igfbp1
Name: insulin-like growth factor binding protein 1
Description: Predicted to have insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Involved in several processes, including aging; insulin receptor signaling pathway; and tissue regeneration. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in diabetic angiopathy. Orthologous to human IGFBP1 (insulin like growth factor binding protein 1); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; insulin-like growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IBP-1; IBP1; IGF-binding protein 1; IGF-BP25; IGFBA; IGFBP-1; insulin-like growth factor-binding protein 1; placental protein 12
Orthologs:
Homo sapiens (human) : IGFBP1 (insulin like growth factor binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Igfbp1 (insulin-like growth factor binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igfbp1 (insulin like growth factor binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IGFBP1 (insulin like growth factor binding protein 1)
Canis lupus familiaris (dog) : IGFBP1 (insulin like growth factor binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igfbp1 (insulin like growth factor binding protein 1)
Sus scrofa (pig) : IGFBP1 (insulin like growth factor binding protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01487,448,716 - 87,453,783 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01481,083,056 - 81,088,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,950,222 - 87,955,289 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11487,969,366 - 87,974,434 (+)NCBI
Celera1481,092,381 - 81,126,760 (+)NCBICelera
Cytogenetic Map14q21NCBI
RH 3.4 Map14605.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Igfbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2872
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.