Gene: Igfbp2 (insulin-like growth factor binding protein 2) Rattus norvegicus
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Symbol: Igfbp2
Name: insulin-like growth factor binding protein 2
Description: Exhibits insulin-like growth factor I binding activity and insulin-like growth factor II binding activity; involved in several processes, including aging, cellular response to hormone stimulus, and female pregnancy; localizes to the apical plasma membrane, cytoplasmic vesicle, and extracellular space; biomarker of hypertension and hypothyroidism; orthologous to human IGFBP2 (insulin like growth factor binding protein 2); PARTICIPATES IN insulin-like growth factor signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BRL-BP; IBP-2; IGF-binding protein 2; IGFBP-2; ILGFBPA; insulin-like growth factor-binding protein 2
Orthologs:
Homo sapiens (human) : IGFBP2 (insulin like growth factor binding protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Igfbp2 (insulin-like growth factor binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igfbp2 (insulin like growth factor binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IGFBP2 (insulin like growth factor binding protein 2)
Canis lupus familiaris (dog) : IGFBP2 (insulin like growth factor binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igfbp2 (insulin like growth factor binding protein 2)
Sus scrofa (pig) : IGFBP2 (insulin like growth factor binding protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0980,118,029 - 80,144,804 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0979,888,642 - 79,915,196 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4971,966,877 - 71,994,211 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1972,113,854 - 72,141,188 (+)NCBI
Celera972,008,814 - 72,036,115 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Igfbp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2873
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.