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Gene: Igfbp2 (insulin-like growth factor binding protein 2) Rattus norvegicus
Symbol: Igfbp2
Name: insulin-like growth factor binding protein 2
Description: Exhibits insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Involved in several processes, including response to estradiol; response to lithium ion; and response to retinoic acid. Localizes to apical plasma membrane; cytoplasmic vesicle; and extracellular space. Biomarker of hypertension and hypothyroidism. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP2 (insulin like growth factor binding protein 2); PARTICIPATES IN insulin-like growth factor signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
Also known as: BRL-BP; IBP-2; IGF-binding protein 2; IGFBP-2; ILGFBPA; insulin-like growth factor-binding protein 2
Homo sapiens (human) : IGFBP2 (insulin like growth factor binding protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Igfbp2 (insulin-like growth factor binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igfbp2 (insulin like growth factor binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IGFBP2 (insulin like growth factor binding protein 2)
Canis lupus familiaris (dog) : IGFBP2 (insulin like growth factor binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igfbp2 (insulin like growth factor binding protein 2)
Sus scrofa (pig) : IGFBP2 (insulin like growth factor binding protein 2)
Chlorocebus sabaeus (African green monkey) : IGFBP2 (insulin like growth factor binding protein 2)
Heterocephalus glaber (naked mole-rat) : Igfbp2 (insulin like growth factor binding protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0980,118,029 - 80,144,804 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl980,118,029 - 80,144,789 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0979,888,642 - 79,915,196 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4971,966,877 - 71,994,211 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1972,113,854 - 72,141,188 (+)NCBI
Celera972,008,814 - 72,036,115 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Igfbp2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2873
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.