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Gene: Il1r1 (interleukin 1 receptor type 1) Rattus norvegicus
Symbol: Il1r1
Name: interleukin 1 receptor type 1
CRRD ID: 2892
Description: Exhibits ionotropic glutamate receptor binding activity. Involved in several processes, including interleukin-1-mediated signaling pathway; positive regulation of neuron migration; and response to odorant. Localizes to several cellular components, including axon; cell surface; and postsynaptic density. Biomarker of pulpitis. Human ortholog(s) of this gene implicated in systemic scleroderma and type 1 diabetes mellitus. Orthologous to human IL1R1 (interleukin 1 receptor type 1); PARTICIPATES IN interleukin-1 signaling pathway; interleukin-12 signaling pathway; apoptotic cell death pathway; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: CD121 antigen-like family member A; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor, type I; interleukin-1 receptor alpha; interleukin-1 receptor type 1; interleukin-1 receptor type I; p80
Homo sapiens (human) : IL1R1 (interleukin 1 receptor type 1)  HGNC  Alliance
Mus musculus (house mouse) : Il1r1 (interleukin 1 receptor, type I)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il1r1 (interleukin 1 receptor type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IL1R1 (interleukin 1 receptor type 1)
Canis lupus familiaris (dog) : IL1R1 (interleukin 1 receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1r1 (interleukin 1 receptor type 1)
Sus scrofa (pig) : IL1R1 (interleukin 1 receptor type 1)
Chlorocebus sabaeus (African green monkey) : IL1R1 (interleukin 1 receptor type 1)
Heterocephalus glaber (naked mole-rat) : Il1r1 (interleukin 1 receptor type 1)
more info ...
Allele / Splice: Il1r1em3Mcwi   Il1r1em2Mcwi   Il1r1em1Mcwi  
Genetic Models: BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em1Mcwi BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0946,962,291 - 47,038,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl946,962,288 - 47,036,670 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,647,422 - 46,723,241 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,434,910 - 39,473,552 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1939,434,750 - 39,475,060 (+)NCBI
Celera940,285,956 - 40,323,730 (+)NCBICelera
Cytogenetic Map9q22NCBI
RH 3.4 Map9396.1RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il1r1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2892
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.