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Gene: Il2rb (interleukin 2 receptor subunit beta) Rattus norvegicus
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Symbol: Il2rb
Name: interleukin 2 receptor subunit beta
Description: Exhibits interleukin-2 binding activity and interleukin-2 receptor activity. Involved in cytokine-mediated signaling pathway and natural killer cell activation. Localizes to the cell surface. Human ortholog(s) of this gene implicated in asthma and myasthenia gravis. Orthologous to human IL2RB (interleukin 2 receptor subunit beta); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; acrylamide; barium sulfate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: high affinity IL-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; IL2RBC; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; interleukin-2 receptor subunit beta; P70-75
Orthologs:
Homo sapiens (human) : IL2RB (interleukin 2 receptor subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Il2rb (interleukin 2 receptor, beta chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il2rb (interleukin 2 receptor subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : IL2RB (interleukin 2 receptor subunit beta)
Canis lupus familiaris (dog) : IL2RB (interleukin 2 receptor subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il2rb (interleukin 2 receptor subunit beta)
Sus scrofa (pig) : IL2RB (interleukin 2 receptor subunit beta)
more info ...
Is Marker For: QTLs:   MAMTS6_H   MAMTS5_H   MAMTS4_H  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07119,701,338 - 119,716,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07119,690,375 - 119,705,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7106,371,243 - 106,385,925 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Il2rb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2896
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.