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Gene: Il3 (interleukin 3) Rattus norvegicus
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Symbol: Il3
Name: interleukin 3
Description: Exhibits cytokine activity and interleukin-3 receptor binding activity. Involved in several processes, including hemopoiesis; positive regulation of cell population proliferation; and regulation of cell growth. Localizes to the extracellular space. Used to study osteosarcoma. Biomarker of prostatic hypertrophy and pyelonephritis. Human ortholog(s) of this gene implicated in Graves' disease; asthma; and rheumatoid arthritis. Orthologous to human IL3 (interleukin 3); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; interleukin-3 signaling pathway; apoptotic cell death pathway; INTERACTS WITH ammonium chloride; bisphenol A; Calcimycin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hematopoietic growth factor; IL-3; interleukin-3; mast cell growth factor; MCGF; multipotential colony-stimulating factor; P-cell-stimulating factor
Orthologs:
Homo sapiens (human) : IL3 (interleukin 3)  HGNC  Alliance
Mus musculus (house mouse) : Il3 (interleukin 3)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : IL3 (interleukin 3)
Canis lupus familiaris (dog) : IL3 (interleukin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il3 (interleukin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01039,620,535 - 39,622,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01039,397,782 - 39,400,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,684,691 - 39,687,041 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,698,313 - 39,700,664 (-)NCBI
Celera1037,746,256 - 37,748,606 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Il3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2897
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.