Gene: Il6r (interleukin 6 receptor) Rattus norvegicus
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Symbol: Il6r
Name: interleukin 6 receptor
Description: Predicted to contribute to ciliary neurotrophic factor receptor activity and interleukin-6 receptor binding activity; involved in several processes, including developmental growth, positive regulation of cell population proliferation, and response to cAMP; localizes to the extracellular space and neuronal cell body membrane; biomarker of several diseases, including congestive heart failure, mental depression, myocardial infarction, orchitis, and sciatic neuropathy; orthologous to human IL6R (interleukin 6 receptor); PARTICIPATES IN interleukin-6 signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-6 receptor subunit alpha; IL-6R 1; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL6R1; Il6ra; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha
Orthologs:
Homo sapiens (human) : IL6R (interleukin 6 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Il6ra (interleukin 6 receptor, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il6r (interleukin 6 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL6R (interleukin 6 receptor)
Canis lupus familiaris (dog) : IL6R (interleukin 6 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il6r (interleukin 6 receptor)
Sus scrofa (pig) : IL6R (interleukin 6 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02189,196,180 - 189,255,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02208,619,391 - 208,679,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,078,049 - 182,128,135 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12182,028,156 - 182,078,238 (-)NCBI
Celera2169,240,233 - 169,289,575 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Il6r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2902
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.