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Gene: Cxcr2 (C-X-C motif chemokine receptor 2) Rattus norvegicus
Symbol: Cxcr2
Name: C-X-C motif chemokine receptor 2
Description: Predicted to have chemokine binding activity and chemokine receptor activity. Involved in several processes, including neutrophil chemotaxis; positive regulation of neutrophil chemotaxis; and regulation of apoptotic process. Predicted to localize to several cellular components, including external side of plasma membrane; mast cell granule; and mitotic spindle. Used to study colitis; demyelinating disease; and nephritis. Biomarker of periapical periodontitis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; acute pyelonephritis; end stage renal failure; and urinary bladder cancer. Orthologous to human CXCR2 (C-X-C motif chemokine receptor 2); INTERACTS WITH 17beta-estradiol; ammonium chloride; benzamide.
Type: protein-coding
Also known as: C-X-C chemokine receptor type 2; chemokine (C-X-C motif) receptor 2; chemokine (C-X-C) receptor 2; Cmkar2; CXC-R2; CXCR-2; GRO/MGSA receptor; high affinity interleukin-8 receptor B; IL-8R B; Il8rb; Interleukin 8 receptor beta; interleukin 8 receptor, beta
Homo sapiens (human) : CXCR2 (C-X-C motif chemokine receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Cxcr2 (chemokine (C-X-C motif) receptor 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CXCR2 (C-X-C motif chemokine receptor 2)
Canis lupus familiaris (dog) : CXCR2 (C-X-C motif chemokine receptor 2)
Sus scrofa (pig) : CXCR2 (C-X-C motif chemokine receptor 2)
Chlorocebus sabaeus (African green monkey) : CXCR2 (C-X-C motif chemokine receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0981,427,275 - 81,435,065 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,427,730 - 81,434,102 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,193,442 - 81,199,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,470,943 - 73,477,315 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1973,617,924 - 73,624,297 (+)NCBI
Celera973,306,852 - 73,313,224 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cxcr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2906
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.