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Gene: Itga1 (integrin subunit alpha 1) Rattus norvegicus
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Symbol: Itga1
Name: integrin subunit alpha 1
Description: Exhibits collagen binding activity and signaling receptor binding activity. Involved in several processes, including activation of MAPK activity; positive regulation of neuron apoptotic process; and vasodilation. Localizes to several cellular components, including the acrosomal vesicle; external side of plasma membrane; and perikaryon. Orthologous to human ITGA1 (integrin subunit alpha 1); PARTICIPATES IN altered integrin mediated signaling pathway; myocardial infarction pathway; integrin mediated signaling pathway; INTERACTS WITH (+)-pilocarpine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD49 antigen-like family member A; integrin alpha 1; integrin alpha-1; integrin, alpha 1; laminin and collagen receptor; VLA-1
Orthologs:
Homo sapiens (human) : ITGA1 (integrin subunit alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Itga1 (integrin alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga1 (integrin subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA1 (integrin subunit alpha 1)
Canis lupus familiaris (dog) : ITGA1 (integrin subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga1 (integrin subunit alpha 1)
Sus scrofa (pig) : ITGA1 (integrin subunit alpha 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0247,127,403 - 47,281,387 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0271,666,601 - 71,823,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4247,107,849 - 47,206,261 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1247,036,084 - 47,134,488 (-)NCBI
Celera242,407,780 - 42,559,904 (-)NCBICelera
Cytogenetic Map2q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itga1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2923
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.