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Gene: Itsn1 (intersectin 1) Rattus norvegicus
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Symbol: Itsn1
Name: intersectin 1
Description: Predicted to have kinase activator activity; molecular adaptor activity; and proline-rich region binding activity. Involved in several processes, including positive regulation of cellular component organization; positive regulation of growth hormone secretion; and regulation of modification of postsynaptic actin cytoskeleton. Localizes to several cellular components, including the clathrin-coated pit; dendrite; and postsynaptic actin cytoskeleton. Orthologous to human ITSN1 (intersectin 1); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: EH domain and SH3 domain regulator of endocytosis 1; EHSH1; intersectin (SH3 domain protein 1A); intersectin 1 (SH3 domain protein 1A); intersectin 1 (SH3 domain protein); intersectin-1; intersection (SH3 domain protein 1A); Itsn
Orthologs:
Homo sapiens (human) : ITSN1 (intersectin 1)  HGNC  Alliance
Mus musculus (house mouse) : Itsn1 (intersectin 1 (SH3 domain protein 1A))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itsn1 (intersectin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ITSN1 (intersectin 1)
Canis lupus familiaris (dog) : ITSN1 (intersectin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itsn1 (intersectin 1)
Sus scrofa (pig) : ITSN1 (intersectin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01131,943,119 - 32,069,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01135,547,331 - 35,672,959 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,721,528 - 31,901,963 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11131,815,217 - 31,903,071 (+)NCBI
Celera1130,687,099 - 30,812,424 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itsn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2935
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.