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Gene: Kcnb1 (potassium voltage-gated channel subfamily B member 1) Rattus norvegicus
Symbol: Kcnb1
Name: potassium voltage-gated channel subfamily B member 1
Description: Exhibits several functions, including ion channel binding activity; protein heterodimerization activity; and voltage-gated potassium channel activity. Involved in several processes, including positive regulation of transport; regulation of motor neuron apoptotic process; and vesicle docking involved in exocytosis. Localizes to several cellular components, including the dendrite membrane; neuronal cell body membrane; and perikaryon. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 26. Orthologous to human KCNB1 (potassium voltage-gated channel subfamily B member 1); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; bisphenol A; cocaine.
Type: protein-coding
Also known as: delayed rectifier potassium channel 1; DRK1; DRK1PC; Kcr1-1; Kv2.1; potassium channel Kv2.1; potassium channel, voltage gated Shab-related subfamily B, member 1; potassium voltage gated channel, Shab-related subfamily, member 1; Shab; voltage-gated potassium channel subunit Kv2.1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03163,850,785 - 163,935,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03170,010,756 - 170,094,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43158,250,001 - 158,345,927 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13158,156,036 - 158,248,459 (-)NCBI
Celera3154,408,682 - 154,493,576 (-)NCBICelera
Cytogenetic Map3q42NCBI
RH 3.4 Map31476.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kcnb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2954
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.