Gene: Kng2 (kininogen 2) Rattus norvegicus
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Symbol: Kng2
Name: kininogen 2
Description: Exhibits cysteine-type endopeptidase inhibitor activity and protease binding activity; involved in negative regulation of T cell proliferation, positive regulation of cell population proliferation, and regulation of protein metabolic process; localizes to the extracellular space, intracellular membrane-bounded organelle, and perikaryon; orthologous to human KNG1 (kininogen 1); PARTICIPATES IN kallikrein-kinin cascade pathway; kinin signaling pathway; syndecan signaling pathway; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 1-octadec-9-enoylglycero-3-phosphate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-1-MAP; K-kininogen; K-kininogen, differential splicing leads to HMW Kngk; kininogen 1; kininogen 1, variant 1; kininogen II; KINKG; KINKH; KINT1G; Kng; Kng1; Kng1_v1; Kng_v1; Kngk; Kngt; Kngt1; LMW T-kininogen I; Map1; T-kininogen; T-kininogen 1; T-kininogen I; thiostatin; Tkg; TKG6
Orthologs:
Homo sapiens (human) : KNG1 (kininogen 1)  HGNC  Alliance
Mus musculus (house mouse) : Kng2 (kininogen 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kng1 (kininogen 1)
Pan paniscus (bonobo/pygmy chimpanzee) : KNG1 (kininogen 1)
Canis lupus familiaris (dog) : KNG1 (kininogen 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kng1 (kininogen 1)
Sus scrofa (pig) : KNG1 (kininogen 1)
more info ...
Allele / Splice: Kng1_v1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01181,509,185 - 81,516,759 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,605,412 - 84,612,986 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,109,499 - 80,131,887 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,167,317 - 80,189,475 (+)NCBI
Celera1176,789,106 - 76,811,459 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kng2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2980
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.