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Gene: Anpep (alanyl aminopeptidase, membrane) Rattus norvegicus
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Symbol: Anpep
Name: alanyl aminopeptidase, membrane
Description: Exhibits aminopeptidase activity and peptide binding activity. Involved in negative regulation of renal sodium excretion; peptide catabolic process; and proteolysis. Localizes to the brush border membrane. Orthologous to human ANPEP (alanyl aminopeptidase, membrane); PARTICIPATES IN angiotensin IV signaling pathway; renin-angiotensin cascade pathway; glutathione metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alanyl (membrane) aminopeptidase; alanyl aminopeptidase; aminopeptidase M; aminopeptidase N; AP-M; AP-N; Apm; APN; cluster of differentiation antigen 13 (CD13); kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; leucine arylaminopeptidase 1; membrane alanine aminopeptidase; microsomal aminopeptidase; rAPN
Orthologs:
Homo sapiens (human) : ANPEP (alanyl aminopeptidase, membrane)  HGNC  Alliance
Mus musculus (house mouse) : Anpep (alanyl (membrane) aminopeptidase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Anpep (alanyl aminopeptidase, membrane)
Pan paniscus (bonobo/pygmy chimpanzee) : ANPEP (alanyl aminopeptidase, membrane)
Canis lupus familiaris (dog) : ANPEP (alanyl aminopeptidase, membrane)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Anpep (alanyl aminopeptidase, membrane)
Sus scrofa (pig) : ANPEP (alanyl aminopeptidase, membrane)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01141,561,364 - 141,604,249 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01142,522,426 - 142,565,721 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,600,751 - 135,619,208 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11135,679,156 - 135,697,614 (-)NCBI
Celera1125,830,648 - 125,849,086 (-)NCBICelera
Cytogenetic Map1q31NCBI
RH 3.4 Map11063.2RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Anpep
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2991
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.