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Gene: Ldha (lactate dehydrogenase A) Rattus norvegicus
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Symbol: Ldha
Name: lactate dehydrogenase A
Description: Exhibits several functions, including L-lactate dehydrogenase activity; NAD binding activity; and identical protein binding activity. Involved in several processes, including response to cAMP; response to estrogen; and response to hydrogen peroxide. Predicted to localize to the cytosol and sperm fibrous sheath. Biomarker of hyperglycemia. Orthologous to human LDHA (lactate dehydrogenase A); PARTICIPATES IN hypoxia inducible factor pathway; cysteine and methionine metabolic pathway; gluconeogenesis pathway; INTERACTS WITH (+)-alpha-tocopherol; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CDK1; L-lactate dehydrogenase A chain; lactate dehydrogenase A-like; LDH muscle subunit; LDH-A; LDH-M; Ldh1; LOC100364670
Orthologs:
Homo sapiens (human) : LDHA (lactate dehydrogenase A)  HGNC  Alliance
Mus musculus (house mouse) : Ldha (lactate dehydrogenase A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ldha (lactate dehydrogenase A)
Pan paniscus (bonobo/pygmy chimpanzee) : LDHA (lactate dehydrogenase A)
Canis lupus familiaris (dog) : LDHA (lactate dehydrogenase A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ldha (lactate dehydrogenase A)
Sus scrofa (pig) : LDHA (lactate dehydrogenase A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01102,900,288 - 102,909,713 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1102,900,286 - 102,909,707 (+)Ensembl
Rnor_5.01103,975,209 - 103,984,638 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4197,403,077 - 97,412,547 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1197,481,187 - 97,490,658 (+)NCBI
Celera191,618,363 - 91,627,752 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ldha
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2996
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.