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Gene: Lhcgr (luteinizing hormone/choriogonadotropin receptor) Rattus norvegicus
Symbol: Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Description: Exhibits several functions, including ATPase binding activity; identical protein binding activity; and peptide hormone binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of adenylate cyclase activity; and arachidonic acid secretion. Localizes to several cellular components, including endosome; intrinsic component of external side of plasma membrane; and lysosome. Human ortholog(s) of this gene implicated in Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Orthologous to human LHCGR (luteinizing hormone/choriogonadotropin receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; peptide and protein hormone signaling pathway; luteinizing hormone signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
Also known as: LH receptor; LH/CG receptor; LH/CG-R; Lhr; LSH-R; LSHR; luteinizing hormone receptor; luteinizing hormone/chorionic gonadotropin receptor; lutropin-choriogonadotropic hormone receptor
Homo sapiens (human) : LHCGR (luteinizing hormone/choriogonadotropin receptor)  HGNC  Alliance
Mus musculus (house mouse) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Canis lupus familiaris (dog) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Sus scrofa (pig) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Chlorocebus sabaeus (African green monkey) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Heterocephalus glaber (naked mole-rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0612,493,182 - 12,554,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl612,493,943 - 12,554,439 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0622,455,216 - 22,516,430 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4612,613,622 - 12,651,587 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1612,613,621 - 12,651,587 (-)NCBI
Celera65,442,191 - 5,504,330 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Lhcgr
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3007
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.