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Gene: Mal (mal, T-cell differentiation protein) Rattus norvegicus
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Symbol: Mal
Name: mal, T-cell differentiation protein
Description: A structural constituent of myelin sheath. Involved in myelination. Localizes to the extrinsic component of membrane and membrane raft. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human MAL (mal, T cell differentiation protein); INTERACTS WITH (20R)-20-hydroxypregn-4-en-3-one; (20S)-20-hydroxypregn-4-en-3-one; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17 kDa myelin vesicular protein; MAL protein gene; MALGENE; MVP17; myelin and lymphocyte protein; myelin and lymphocyte protein, T-cell differentiation protein; NS 3; T-lymphocyte maturation-associated protein
Orthologs:
Homo sapiens (human) : MAL (mal, T cell differentiation protein)  HGNC  Alliance
Mus musculus (house mouse) : Mal (myelin and lymphocyte protein, T cell differentiation protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mal (mal, T cell differentiation protein)
Pan paniscus (bonobo/pygmy chimpanzee) : MAL (mal, T cell differentiation protein)
Canis lupus familiaris (dog) : MAL (mal, T cell differentiation protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101963404 (myelin and lymphocyte protein)
Sus scrofa (pig) : MAL (mal, T cell differentiation protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03120,209,647 - 120,233,655 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03127,099,278 - 127,123,286 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43115,166,671 - 115,190,432 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13115,072,243 - 115,096,005 (-)NCBI
Celera3113,699,325 - 113,723,029 (-)NCBICelera
Cytogenetic Map3q36NCBI
RH 3.4 Map3998.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mal
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3037
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.