Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Man2b1 (mannosidase, alpha, class 2B, member 1) Rattus norvegicus
Analyze
Symbol: Man2b1
Name: mannosidase, alpha, class 2B, member 1
Description: Exhibits alpha-mannosidase activity and mannose binding activity. Predicted to be involved in learning or memory; mannose metabolic process; and protein deglycosylation. Localizes to the lysosome. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Orthologous to human MAN2B1 (mannosidase alpha class 2B member 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lysosomal alpha-mannosidase; Manb; mannosidase 2, alpha B1; Mannosidase, alpha B, lysosomal; MGC72561; similar to mannosidase 2, alpha B1
Orthologs:
Homo sapiens (human) : MAN2B1 (mannosidase alpha class 2B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Man2b1 (mannosidase 2, alpha B1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Man2b1 (mannosidase alpha class 2B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAN2B1 (mannosidase alpha class 2B member 1)
Canis lupus familiaris (dog) : MAN2B1 (mannosidase alpha class 2B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Man2b1 (mannosidase alpha class 2B member 1)
Sus scrofa (pig) : MAN2B1 (mannosidase alpha class 2B member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01926,196,797 - 26,216,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,196,837 - 26,216,267 (+)Ensembl
Rnor_5.01937,172,434 - 37,191,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,711,378 - 24,730,659 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,716,204 - 24,735,485 (-)NCBI
Celera1922,613,060 - 22,632,343 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Man2b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3039
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.