Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Maob (monoamine oxidase B) Rattus norvegicus
Analyze
Symbol: Maob
Name: monoamine oxidase B
Description: Exhibits flavin adenine dinucleotide binding activity; identical protein binding activity; and primary amine oxidase activity. Involved in several processes, including negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; and response to corticosterone. Localizes to the mitochondrial outer membrane. Biomarker of Parkinson's disease and cholestasis. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human MAOB (monoamine oxidase B); PARTICIPATES IN citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; Parkinson's disease pathway; INTERACTS WITH (+)-schisandrin B; (-)-selegiline; (3,4-dihydroxyphenyl)acetic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amine oxidase [flavin-containing] B; MAO-B; monoamine oxidase type B; monoamine oxidase-B
Orthologs:
Homo sapiens (human) : MAOB (monoamine oxidase B)  HGNC  Alliance
Mus musculus (house mouse) : Maob (monoamine oxidase B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Maob (monoamine oxidase B)
Pan paniscus (bonobo/pygmy chimpanzee) : MAOB (monoamine oxidase B)
Canis lupus familiaris (dog) : MAOB (monoamine oxidase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Maob (monoamine oxidase B)
Sus scrofa (pig) : MAOB (monoamine oxidase B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X6,430,694 - 6,533,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX6,430,594 - 6,533,534 (+)Ensembl
Rnor_5.0X7,249,779 - 7,352,270 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X17,553,529 - 17,657,852 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X17,606,846 - 17,711,170 (+)NCBI
CeleraX6,397,919 - 6,500,914 (+)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Maob
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3041
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.