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Gene: Mapk3 (mitogen activated protein kinase 3) Rattus norvegicus
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Description: Exhibits ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including arachidonic acid metabolic process; decidualization; and protein phosphorylation. Localizes to several cellular components, including caveola; cytosol; and nucleoplasm. Used to study gastric ulcer; middle cerebral artery infarction; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ceramide signaling pathway; endothelin signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-dihydromyricetin.
Type: protein-coding
Also known as: Erk-1; ERK1; ERT2; Esrk1; extracellular signal-regulated kinase 1; extracellular-signal-regulated kinase 1; insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAPK 1; MAPK 3; MAPK1; microtubule-associated protein 2 kinase; mitogen activated kinase 3; mitogen-activated 3; mitogen-activated 3 (MAP kinase 3, p44); mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MNK1; p44; p44-ERK1; p44-MAPK; p44erk1; p44mapk; Prkm3; Protein kinase mitogen activated 3 (extracellular-signal-regulated kinase 1 ERK1); Protein kinase, mitogen activated 3 (extracellular-signal-regulated kinase 1, ERK1)
Homo sapiens (human) : MAPK3 (mitogen-activated protein kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Mapk3 (mitogen-activated protein kinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk3 (mitogen-activated protein kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK3 (mitogen-activated protein kinase 3)
Canis lupus familiaris (dog) : MAPK3 (mitogen-activated protein kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk3 (mitogen-activated protein kinase 3)
Sus scrofa (pig) : MAPK3 (mitogen-activated protein kinase 3)
Chlorocebus sabaeus (African green monkey) : MAPK3 (mitogen-activated protein kinase 3)
Heterocephalus glaber (naked mole-rat) : Mapk3 (mitogen-activated protein kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01198,192,773 - 198,198,975 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,192,773 - 198,198,975 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,172,641 - 205,178,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,935,044 - 185,941,245 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,084,924 - 186,091,127 (+)NCBI
Celera1179,022,318 - 179,028,386 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)