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Gene: Tpsab1 (tryptase alpha/beta 1) Rattus norvegicus
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Symbol: Tpsab1
Name: tryptase alpha/beta 1
Description: Predicted to have identical protein binding activity and serine-type endopeptidase activity. Predicted to be involved in extracellular matrix disassembly and proteolysis. Predicted to localize to the extracellular space and mast cell granule. Orthologous to human TPSAB1 (tryptase alpha/beta 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mast cell protease 7; Mcpt7; MMCP-7; rMCP-7; TPSB1; tryptase; tryptase alpha/beta-1; tryptase beta 1; tryptase, skin
Orthologs:
Homo sapiens (human) : TPSAB1 (tryptase alpha/beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Tpsab1 (tryptase alpha/beta 1)  MGI  Alliance
Sus scrofa (pig) : LOC110255206 (tryptase-like)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01014,701,253 - 14,703,668 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01014,519,181 - 14,521,596 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,591,590 - 14,594,005 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11014,591,590 - 14,594,005 (-)NCBI
Celera1014,032,330 - 14,034,745 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tpsab1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3066
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.